Cyclic nucleotides

Bioactive triterpenoids fromVochysia pacifica interact with cyclic nucleotide phosphodiesterase isozyme PDE4

Biological Sciences / Phytotherapy / Humans / Myrtaceae / CHEMICAL SCIENCES / Phosphodiesterase Inhibitors / Plant extracts / Isoenzymes / Cyclic nucleotides / Triterpenes / Phosphodiesterase Inhibitors / Plant extracts / Isoenzymes / Cyclic nucleotides / Triterpenes

Compartmentalized phosphodiesterase-2 activity blunts β-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway

Calcium / Signal Transduction / Mice / cyclic AMP / Nitric oxide / Animals / Feedback Control / Norepinephrine / Clinical Sciences / Phosphodiesterase Inhibitors / Rats / Cyclic nucleotides / Circulation / Adenine / cyclic GMP / Adenylyl Cyclase / Isoproterenol / Animals / Feedback Control / Norepinephrine / Clinical Sciences / Phosphodiesterase Inhibitors / Rats / Cyclic nucleotides / Circulation / Adenine / cyclic GMP / Adenylyl Cyclase / Isoproterenol

Biophysical Characterization of Cyclic Nucleotide Phosphodiesterases

Protein Folding / Fluorescence / Arabidopsis thaliana / Saccharomyces cerevisiae / Circular Dichroism / Escherichia coli / Urea / Biochemical / Arabidopsis / Phosphodiesterase Inhibitors / Cyclic nucleotides / Isothermal Titration Calorimetry / Calorimetry / Enzymatic Activity / X Ray Crystallography / Protein Denaturation / Biochemistry and cell biology / Molecular Sequence Data / Escherichia coli / Urea / Biochemical / Arabidopsis / Phosphodiesterase Inhibitors / Cyclic nucleotides / Isothermal Titration Calorimetry / Calorimetry / Enzymatic Activity / X Ray Crystallography / Protein Denaturation / Biochemistry and cell biology / Molecular Sequence Data

In Central Obesity, Weight Loss Restores Platelet Sensitivity to Nitric Oxide and Prostacyclin

Obesity / Multidisciplinary / Insulin Resistance / Adipose tissue / Humans / Platelet aggregation / Weight Loss / cyclic AMP / Nitric oxide / Female / Male / Vascular endothelium / Endothelial dysfunction / Platelet activation mechanism / Platelet function / Adult / Central Obesity / Cyclic nucleotides / Body Weight / cyclic GMP / Adenosine Diphosphate / Sodium Nitroprusside / Platelet aggregation / Weight Loss / cyclic AMP / Nitric oxide / Female / Male / Vascular endothelium / Endothelial dysfunction / Platelet activation mechanism / Platelet function / Adult / Central Obesity / Cyclic nucleotides / Body Weight / cyclic GMP / Adenosine Diphosphate / Sodium Nitroprusside

Differential inhibition of mesangial MAP kinase cascade by cyclic nucleotides

Enzyme Inhibitors / Signal Transduction / Protein Kinases / Kidney / cyclic AMP / Animals / Peptides / Mitogen Activated Protein Kinase / Clinical Sciences / Rats / Cyclic nucleotides / Endothelin-1 / MAP Kinase / cyclic GMP / Animals / Peptides / Mitogen Activated Protein Kinase / Clinical Sciences / Rats / Cyclic nucleotides / Endothelin-1 / MAP Kinase / cyclic GMP

Cyclic nucleotide phosphodiesterase 3A–deficient mice as a model of female infertility

Enzyme Inhibitors / Humans / Meiosis / Mice / cyclic AMP / Female / Ovulation / Animals / Clinical / Phosphodiesterase Inhibitors / Isoenzymes / Cyclic nucleotides / Ovary / Oocytes / Female Infertility / Clinical Investigation / Female / Ovulation / Animals / Clinical / Phosphodiesterase Inhibitors / Isoenzymes / Cyclic nucleotides / Ovary / Oocytes / Female Infertility / Clinical Investigation

D020 The polyphenol curcumin inhibits in vitro angiogenesis and cyclic nucleotide phosphodiesterases (PDEs) activities similarly to PDE inhibitors

Clinical Sciences / Phosphodiesterase Inhibitors / Cyclic nucleotides

Endothelin-1 decreases microvascular fluid leak via second messenger cyclic nucleotides and protein kinase a signal transduction

Signal Transduction / Clinical Sciences / Cyclic nucleotides / Standard Error / Surgical / Second Messengers

Biophysical Characterization of Cyclic Nucleotide Phosphodiesterases

Protein Folding / Fluorescence / Arabidopsis thaliana / Saccharomyces cerevisiae / Circular Dichroism / Escherichia coli / Urea / Biochemical / Arabidopsis / Phosphodiesterase Inhibitors / Cyclic nucleotides / Isothermal Titration Calorimetry / Calorimetry / Enzymatic Activity / X Ray Crystallography / Protein Denaturation / Biochemistry and cell biology / Escherichia coli / Urea / Biochemical / Arabidopsis / Phosphodiesterase Inhibitors / Cyclic nucleotides / Isothermal Titration Calorimetry / Calorimetry / Enzymatic Activity / X Ray Crystallography / Protein Denaturation / Biochemistry and cell biology

Plasma cyclic nucleotide levels in acute leukemia patients

Leukemia / Adolescent / Acute Myeloid Leukemia / Humans / cyclic AMP / Female / Blood / Male / Clinical Sciences / Aged / Middle Aged / Adult / Cyclic nucleotides / cyclic GMP / Female / Blood / Male / Clinical Sciences / Aged / Middle Aged / Adult / Cyclic nucleotides / cyclic GMP

Plasma cyclic nucleotide levels in acute leukemia patients

Leukemia / Adolescent / Acute Myeloid Leukemia / Humans / cyclic AMP / Female / Blood / Male / Clinical Sciences / Aged / Middle Aged / Adult / Cyclic nucleotides / cyclic GMP / Female / Blood / Male / Clinical Sciences / Aged / Middle Aged / Adult / Cyclic nucleotides / cyclic GMP

Compartmentalized Phosphodiesterase-2 Activity Blunts -Adrenergic Cardiac Inotropy via an NO/cGMP-Dependent Pathway

Calcium / Signal Transduction / Mice / cyclic AMP / Nitric oxide / Animals / Feedback Control / Norepinephrine / Clinical Sciences / Phosphodiesterase Inhibitors / Rats / Cyclic nucleotides / Circulation / Adenine / cyclic GMP / Adenylyl Cyclase / Isoproterenol / Animals / Feedback Control / Norepinephrine / Clinical Sciences / Phosphodiesterase Inhibitors / Rats / Cyclic nucleotides / Circulation / Adenine / cyclic GMP / Adenylyl Cyclase / Isoproterenol

Cyclic nucleotide phosphodiesterase isoenzyme activities in human alveolar macrophages

Immunology / Phosphodiesterase Inhibitors / Public health systems and services research / Cyclic nucleotides / Alveolar Macrophage

Mammalian 2\',3\' cyclic nucleotide phosphodiesterase (CNP) can function as a tRNA splicing enzyme in vivo

RNA / Saccharomyces cerevisiae / Mutation / Animals / Enzyme / Phosphodiesterase Inhibitors / Rats / Cyclic nucleotides / Biochemistry and cell biology / Phosphodiesterase Inhibitors / Rats / Cyclic nucleotides / Biochemistry and cell biology

Biophysical Characterization of Cyclic Nucleotide Phosphodiesterases

Protein Folding / Fluorescence / Arabidopsis thaliana / Saccharomyces cerevisiae / Circular Dichroism / Escherichia coli / Urea / Biochemical / Arabidopsis / Phosphodiesterase Inhibitors / Cyclic nucleotides / Isothermal Titration Calorimetry / Calorimetry / Enzymatic Activity / X Ray Crystallography / Protein Denaturation / Biochemistry and cell biology / Molecular Sequence Data / Escherichia coli / Urea / Biochemical / Arabidopsis / Phosphodiesterase Inhibitors / Cyclic nucleotides / Isothermal Titration Calorimetry / Calorimetry / Enzymatic Activity / X Ray Crystallography / Protein Denaturation / Biochemistry and cell biology / Molecular Sequence Data

Biophysical Characterization of Cyclic Nucleotide Phosphodiesterases

Protein Folding / Fluorescence / Arabidopsis thaliana / Saccharomyces cerevisiae / Circular Dichroism / Escherichia coli / Urea / Biochemical / Arabidopsis / Phosphodiesterase Inhibitors / Cyclic nucleotides / Isothermal Titration Calorimetry / Calorimetry / Enzymatic Activity / X Ray Crystallography / Protein Denaturation / Biochemistry and cell biology / Molecular Sequence Data / Escherichia coli / Urea / Biochemical / Arabidopsis / Phosphodiesterase Inhibitors / Cyclic nucleotides / Isothermal Titration Calorimetry / Calorimetry / Enzymatic Activity / X Ray Crystallography / Protein Denaturation / Biochemistry and cell biology / Molecular Sequence Data

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